The Best Glucosamine for Dogs

One of the more difficult aspects of dog ownership is bearing witness to the aging process. Dogs, like humans, have joints that can wear down over time making mobility painful and challenging. Fortunately there are some helpful options.

One common remedy is a glucosamine supplement. Glucosamine is a natural compound that aids in pain relief by supporting joint-lining cartilage. Glucosamine comes in many forms and can include many different active and inactive ingredients. We’ve reviewed many of the top glucosamine supplements and compared all the common forms and ingredients. If your Vet has given you the go ahead to try a glucosamine supplement for your pup, keep reading to see what might work best for you.

For other helpful and healthy aging resources, check out our articles on dog ramps, vitamins, and probiotics.

Best Glucosamine for Dogs Overall
Cosequin DS Maximum Strength
Cosequin DS is our top overall glucosamine supplement for dogs.

Cosequin DS is a high-quality glucosamine joint supplement if your pup is having trouble performing activities like running or jumping. Cosequin Maximum Strength gets our top nod due to the reasonable price and very many positive reviews. Cosequin has helped many a dog return to better movement.

The 5 Top-Rated Glucosamine Supplements for Dogs

Editor's PicksBrandRating
Best Glucosamine for Dogs OverallCosequin Maximum Strength4.7
Best Glucosamine Chews for DogsZesty Paws Multivitamin4.6
Best Budget Glucosamine for DogsPetNC Natural Care4.5
Best Hemp Glucosamine for DogsPethonesty Hemp Hip & Joint Supplement4.7
Best Liquid Glucosamine for DogsTerraMax Pro4.4

Best Glucosamine for Dogs Overall: Cosequin DS Maximum Strength

If your vet has recommended a glucosamine supplement to help your dog get back to running, jumping, and climbing like she used to, then Cosequin DS Maximum Strength is a great product to try. Manufactured with glucosamine, chondroitin, and methylsufonylmethane (MSM), this ingredient combination eases your pup’s joint pain and helps to support healthy cartilage.

Produced in the USA since 1992, Nutramax claims that Cosequin has been shown to be safe and effective in peer-reviewed veterinary journals. We always recommend consulting with your Vet before trying any new supplement.

Cosequin DS is available in three sizes ranging from 60-250 soft chews per package, and you also have the choice between soft chews and chewable tablets. Nutramax also provides detailed dosing instructions for you to review with your Vet.

Cosequin’s reviews are overwhelmingly positive, but be on the lookout for the knockoff products that some reviewers have purchased.

Cosequin DS Maximum Strength Key Features:

  • Manufactured with glucosamine, chondroitin, and MSM
  • Made in the USA
  • 3 size packages to choose from
  • Available in soft chews or chewable tablets
  • Per Nutramax, have been shown to be safe and effective in Veterinary journals

Best Glucosamine Chews for Dogs: Zesty Paws Multivitamin

Best Glucosamine Chews for Dogs
Zesty Paws Multivitamin
Zesty Paws is our top glucosamine soft chew.

Our favorite glucosamine supplement soft chew is Zesty Paws Multivitamins for Dogs. This multivitamin is a daily 5-1 chewable treat with ingredients that support your dog’s skin, coat, joints, heart, digestive organs, and immune system — so pretty much a one-stop shop for better health.

Zesty Paws uses a distilled form of MSM that works in combination with glucosamine and chondroitin to support joint function, vitamin E and cod liver oil for healthy skin and coat, probiotics to enrich the digestive system, and multiple vitamins that support the heart and immune system. In total, Zesty Paws provides over 35 vitamins, nutrients, and minerals in these chewable bites.

Sold with 90 chews per package, dosing is recommended from 1-3 chews per day depending on the size of your dog. Check with your Vet for specific details. If you prefer dial in on a specific supplement rather than this all-in-one multivitamin, Zesty Paws sells numerous other supplements as well. The few negative reviews of this product mention that the multivitamin gives their dog diarrhea, but overall the response is very positive.

Zesty Paws Multivitamin Key Features:

  • 5-1 daily multivitamin
  • Supports healthy joints, heart, digestive system, immune function, skin and coat
  • Over 35 vitamins, nutrients, and minerals for your dog’s health
  • Contains joint friendly MSM, chondroitin, and glucosamine
  • 90 count package
  • Dosing recommended from 1-3 soft chews per day depending on size

Best Budget Glucosamine for Dogs: PetNC Natural Care Hip & Joint

Best Budget Glucosamine for Dogs
Pet NC Natural Care Hip and Joint
Pet NC is a budget-friendly glucosamine supplement for your pooch.

Our budget pick, PetNC Natural Care Hip & Joint, packs in many of the same ingredients found in our other top choices at about one-third of the cost. You’ll find the major joint care supplements: glucosamine, chondroitin, and MSM, as well as many other natural ingredients combined into these soft chews. The inactive ingredients are listed on the Amazon page for full transparency.

PetNC provides a package of 90 soft chews with detailed dosing instructions depending on the size of your pup. PetNC states that their products are laboratory tested, veterinarian-formulated, and they are made in the USA.

PetNC certifies the purity of their products by using ISO laboratory standards, and Natural Care Hip & Joint carry the National Animal Council Supplement (NASC) quality seal to ensure you are purchasing a product from a reputable manufacturer. The focus here is on quality, not cost.

PetNC Natural Care Hip & Joint Key Features

  • Active ingredients include glucosamine, chondroitin, and MSM
  • 90 soft chews per package
  • Detailed dosing instructions
  • Manufactured in ISO certified laboratories
  • Carries the NASC quality seal
  • Made in the USA

Best Hemp Glucosamine for Dogs: Pet Honesty Hemp Hip & Joint Supplement

Best Hemp Glucosamine for Dogs
Pet Honesty Hemp Hip & Joint Supplement
Pet Honesty uses hemp oil to ease pain and inflammation.

Pet Honesty uses glucosamine combined with organic anti-inflammatories hemp oil and turmeric to promote mobility. They proudly use organic products, and do not include any corn, wheat, GMO, or sugar in their soft chews.

Each package contains 90 soft chews, and while you may pay slightly more for the product, Pet Honesty claims that their chews are so effective that they will last longer than competitors’ products.

Pet Honesty Hemp comes in bacon or duck flavors, so no more hiding tablets in your pup’s regular food. 9 out of 10 dogs gobbled up these chews unassisted, so you be pretty confident your pup will like the taste.

Each chew contains MSM, chondroitin, and several other natural ingredients in addition to hemp oil, turmeric, and glucosamine. Check out the components before you buy to make sure your dog isn’t allergic. Pet Honesty products are made in the USA.

Pet Honesty Hemp & Hip Joint Supplement Key Features:

  • Manufatured with anti-inflammatory hemp oil
  • Contains turmeric, glucosamine, MSM, chondroitin
  • Tasty bacon and duck flavors
  • Each package contains 90 soft chews
  • Made in the USA

Best Liquid Glucosamine for Dogs: TerraMax Pro

Best Liquid Glucosamine for Dogs
TerraMax Pro Hip & Joint Supplement
Check out TerraMax Pro for a liquid glucosamine supplement.

TerraMax Pro contains glucosamine, MSM, chondroitin, and hyaluronic acid to help keep your older dog’s joints limber. This is a 100% all-natural product that is made in the USA, and TerraMax offers a full unconditional refund to guarantee your satisfaction.

Most of the glucosamine supplements are soft chews or tablets, but there are a few reasons why a liquid supplement might be preferable. Liquids make it easier to adjust the dosage, you can easily just mix it in the regular food or water bowl, and some dogs just may not like the soft chews.

While side effects are rare, some dogs may experience diarrhea or vomiting which may require a dosage adjustment. As always, consult with your Vet before staring a new supplement.

TerraMax Pro Key Features:

  • Liquid supplement
  • Contains glucosamine, chondroitin, MSM, and hyaluronic acid
  • All-natural ingredients
  • 100% unconditional refund offered
  • Made in the USA

Who Should Buy Glucosamine for Dogs

Just like humans, as dogs age their joints can become painful and stiff causing pain while running, jumping, or walking. Glucosamine is a naturally occurring compound that can help develop and maintain cartilage — a spongy tissue that cushions our joints. In addition to supporting cartilage, glucosamine is also thought to reduce painful inflammation as well.

Other predominant ingredients you’ll find in pain reducing supplements are methylsufonylmethane (MSM) and chondroitin. MSM is a dietary sulfur that promotes healthy cellular activity. It is thought to reduce inflammation and therefore relieve pain.

Like glucosamine, chondroitin is a natural substance that supports healthy cartilage. It’s a popular supplement to combat pain from arthritis or hip dysplasia in your pup.

Please note that none of these supplements are regulated by the Food & Drug Administration (FDA), they vary in quality, and they can have side effects. We recommend that you consult with your Veterinarian before trying any new supplement.

Best Glucosamine for Dogs Overall
Cosequin DS Maximum Strength
Cosequin DS is our top overall glucosamine supplement for dogs.

Important Features to Consider

Glucosamine for dogs should have a few important features. Here is what to consider when selecting a glucosamine supplement for your dog.

  • Quality control measures. Since these supplements are edible and can have side-effects on your dog, you want to spend some time researching the quality of both the ingredients and the production technique. You can find this information in the product description, by the reviews, and by searching online. Your Vet may be familiar with many of the top products as well.
  • Type of supplement. Although the predominant glucosamine supplement is a soft chew, there are also liquid, powder, and tablet forms which can be purchased depending on your preference. Liquids and powders make it easier to adjust dosage, while soft chews can be fed along with regular food or given as a treat.
  • Active & inactive ingredients. None of the supplements are pure glucosamine; they all contain some active and inactive ingredients. You should do some research to ensure your dog isn’t sensitive or allergic to any of the compounds, and also to be sure that you are comfortable with your pet ingesting the various components. Some of the glucosamine supplements are all-natural, but these are not regulated by the Food & Drug Administration. It helps to do some homework here.

Frequently Asked Questions

What is glucosamine for dogs, and how does it work?

Glucosamine is a naturally occurring sugar protein that helps to build cartilage in our joints. Cartilage is a springy tissue that cushions and protects our bones and joints. As dogs age, cartilage can wear out and eventually cause pain during activities. Glucosamine supplements can help promote healthy cartilage, and reduce joint pain in your pup.

How much glucosamine should you give to a dog?

All of the manufacturers should include dosage recommendations with their products, and the amount will vary by age or how much your dog weighs. If the package does not include dosing instructions, then call the manufacturer or look for another brand. Also, note that most glucosamine supplements are not regulated, so you should always touch base with your Vet before giving any supplement to your dog.

Once your dog begins taking glucosamine, keep a very close eye on her for the first few days and look for signs that she may not be adjusting to the new regimen. Look out for signs of trouble like difficulty breathing, excess fatigue, vomiting, and diarrhea, and have the Vet on standby if you see any of these issues.

Can I give my dog human glucosamine?

While the glucosamine formula is similar for both humans and dogs, the challenge is dialing in the correct dose as people will usually need more per dose than pups. Glucosamine for humans may also contain some salts that don’t sit well with canines. This is certainly something that you should ask your Vet.

At what age should you give your dog glucosamine?

There is no hard and fast rule here except that you should wait until your dog’s body has completely stopped growing at approximately 12 months. Most dogs won’t need joint supplements until they are much older, but breeds like hounds and bulldogs tend to have more joint issues earlier in life. As always, you should discuss with your Vet to determine if and when to start glucosamine supplements.

Other Products We Reviewed

Best Glucosamine for Dogs Overall
Cosequin DS Maximum Strength
Cosequin DS is our top overall glucosamine supplement for dogs.

We looked at 20 other glucosamine supplements for your dog. Although they didn’t make the top 5 list, they are products worthy of review and consideration. The information you need to compare each one is included in the listing.

Glucosamine Soft Chews

Doggie Daily Glucosamine

Doggie Dailies

Doggie Daily packages 225 soft chews in each bottle, and you can choose from peanut butter or chicken flavors. Each chew contains six active ingredients to support your dog’s health, and Doggie Daily products are made in the USA.

Key Features:

  • 225 soft chews
  • Chicken or peanut butter flavors
  • Six active ingredients
  • Made in the USA
  • Every batch is tested by an independent lab

VetIQ Maximum Strength Hip and Joint Supplement

Vet IQ Maximum Strength

Each soft chew in this 180 count package contains glucosamine, MSM, and krill to support your pup’s joints and alleviate pain. VetIQ Maximum Strength soft chews are chicken-flavored, and their products are made in the USA.

Key Features:

  • 180 soft chews per package
  • Active ingredients include glucosamine, MSM, and krill
  • Chicken-flavored
  • Made in the USA

Vetriscience Laboratories Glycoflex 3

Vetriscience Glycoflex

Vetriscience states that its Glycoflex 3 product has been clinically proven to increase hind leg strength in as little as 4 weeks. This is the third stage joint support product, and is designed for working breeds and active dogs.

Key Features:

  • Ingredients include glucosamine, MSM, and green-lipped mussel
  • 120 bite-sized chews per package
  • Chicken or duck flavors
  • Designed for very active dogs

Glucosamine with Chondroitin

Active Chews Premium

Active Chews Advanced

Active Chews Premium joint support tablets use glucosamine, chondroitin, MSM, and turmeric to give your pooch some pain relief. These soft chews are manufactured at a FDA registered facility and Active Chews claims that their “no heat, no cook” process guarantees 100% potency of the active ingredients.

Key Features:

  • Ingredients include glucosamine, chondroitin, MSM, and turmeric
  • Chicken flavored soft chews
  • “No heat, no cook” production to provide maximum potency
  • Made in the USA at a FDA registered facility

NaturVet ArthriSoothe Gold

Natruvet Arisoothe Gold

Active ingredients in this NaturVet product include glucosamine, chondroitin, MSM, and green-lipped mussel. This is NaturVet’s level 3 advanced joint relief product, and it is recommended for senior dogs and those recovering from injury.

Key Features:

  • Contains glucosamine, chondroitin, MSM, and green-lipped mussel
  • Level 3 product recommended for advanced joint relief
  • Package options include 70 or 180 soft chews
  • Wheat free, NASC, cGMP compliant
  • Made in the USA

NaturVet Glucosamine DS Plus

Naturvet Glucosamine DS Plus

NaturVet recommends their level 2 product for larger breeds and dogs that are overweight. In addition to glucosamine, the DS Plus product contains chondroitin, MSM, and antioxidants to support your pup’s joint health.

Key Features:

  • Contains glucosamine, MSM, chondroitin, and antioxidants
  • Level 2 product recommended for large breeds and overweight dogs
  • Package options include 70 or 120 flavored soft chews
  • Wheat free, NASC, cGMP compliant
  • Made in the USA

NaturVet Senior Wellness

Naturvet Senior Wellness

As the product name states, NaturVet Senior Wellness is specifically designed for older dogs. Senior Wellness is formulated with glucosamine, MSM, and chondroitin to support healthy aging and pain-free movement.

Key Features:

  • Formulated for older dogs
  • Ingredients include glucosamine, MSM, and chondroitin
  • Packaging options include 40, 90, or 120 time-release tablets
  • Time-release tablets allow active ingredients to slowly and steadily enter your older pup’s bloodstream
  • NASC, cGMP compliant
  • Made in the USA

Nootie Glucosamine Chondroitin for Dogs

Nootie Glucosamine

Active ingredients in Nootie’s joint supplement include glucosamine, chondroitin, MSM, hyaluronic acid, and turmeric. Packaged with 250 soft chews, Nootie Glucosamine is made in the USA.

Key Features:

  • Formulated with glucosamine, chondroitin, MSM, hyaluraonic acid, and turmeric
  • 250 soft chews with detailed dosing instructions
  • Suitable for all sizes and breeds
  • Made in the USA

Paws & Pals Glucosamine

paws and pals glucosamine

Active ingredients in Paws & Pals soft chews include glucosamine, chondroitin, MSM, and yucca schidigera. Each package contains 240 soft chews and detailed dosing instructions for dogs of all sizes.

Key Features:

  • Contains glucosamine, chondroitin, MSM, and yucca schidigera
  • 240 soft chews
  • For dogs of all sizes
  • Wheat free
  • Made in the USA in a FDA regulated facility

Petaxin Glucosamine for Dogs

Petaxin Glucosamine

With Petaxin, you get 120 soft chews formulated with glucosamine, MSM, chondroitin, turmeric and yucca to help your dog stay active and pain free. Petaxin also contains vitamins C and E for immune system support.

Key Features:

  • 120 soft chews
  • Contains glucosamine, chondroitin, MSM, turmeric, and yucca extract
  • Other ingredients include vitamins C and E
  • Beef flavor
  • No corn, wheat, or grain
  • Made in the USA

Pethonesty Glucosamine for Dogs

Pethonesty Advanced

Pethonesty uses a superfood base of carrots, sweet potatoes, and tomatoes to keep their soft chews nutritious. Active ingredients include glucosamine, chondroitin, MSM, yucca, and turmeric.

Key Features:

  • 90 soft chews
  • Contain glucosamine, chondroitin, yucca, and turmeric
  • Nutritious base of sweet potatoes, tomatoes, and carrots
  • No sugar, wheat, corn, GMOs, or preservatives
  • Made in the USA

PointPet Glucosamine for Dogs

PointPet All Natural

In addition to cartilage supporting chondroitin, PointPet packs glucosamine, MSM, yucca, omega 3, omega 6, vitamin C, and vitamin E into each soft chew. PointPet provides a 100% satisfaction guarantee.

Key Features:

  • 90 or 120 soft chews package options
  • Contains natural vitamins and omega fatty acids
  • 100% satisfaction guarantee
  • Made in the USA in a FDA registered facility

Prosense Hip & Joint Solutions

Prosense Hip & Joint Solutions

Although the Prosense packages only contain 60 soft chews, you can currently purchase a pack on Amazon for under $5 — making these the most economical of all the products we’ve reviewed.

  • 60 soft chews per package
  • Contains glucosamine, MSM, chondroitin, vitamin C
  • Detailed dosing instructions
  • NASC quality seal
  • Made in the USA

Glucosamine with Hemp

GoodGrowlies Hemp Chews

GoodGrowlies Hemp Chews

GoodGrowlies Hemp Chews are healthy, safe, effective, and made in the USA. Hemp seed oil works in combination with glucosamine, chondroitin, MSM, and turmeric to reduce joint pain and improve mobility.

Key Features:

  • 120 soft chews per pack
  • Active ingredients include hemp seed oil, glucosamine, chondroitin, MSM, turmeric
  • Made in the USA
  • Does not contain sugar, dairy, corn, or soy-derived products

StrellaLab Hemp Treats

StrellaLabs Hemp Treats

StrellaLab adds organic hempseed oil to this product to improve your dog’s energy and reduce joint pain. Other active ingredients include glucosamine, chondroitin, MSM, and turmeric.

Key Features:

  • Contains hempseed oil
  • Other active ingredients include glucosamine, turmeric, chondroitin, and MSM
  • Safe for all ages
  • Contains 120 soft chews per jar
  • Made in the USA
  • Does not contain corn, soy, sugar, or other artificial flavorings

Veterinary Naturals Hemp & Hip Supplements

Veterinary Naturals Hemp & Hips

Veterinary Naturals formulated the product specifically for your large-breed senior dog. More than just a glucosamine product, these soft chews also contain hemp oil and omega fatty acids to relieve pain and assist with joint mobility.

Key Features:

  • Formulated specifically for large-breed senior dogs
  • Contains glucosamine, chondroitin, hemp oil, and omega fatty acids
  • 60 soft chews per package
  • Bacon or chicken flavors

Glucosamine Tablets

Coco and Luna Glucosamine for Dogs

Coco & Luna glucosamine

This all-natural chewable tablet contains glucosamine, MSM, chondroitin, and manganese. Safe for all ages, the manufacturer supports a full 100% money back guarantee.

Key Features:

  • 120 chewable tablets per package
  • Contains glucosamine, MSM, chondroitin, and manganese
  • 100% money-back guarantee
  • All-natural ingredients
  • Made in the USA

Prosense Glucosamine for Dogs

Prosense Advanced Strength

Glucosamine tablets are a good option when your pooch doesn’t like the soft chew treats. Prosense tablets contain the same joint pain relieving ingredients that the soft chews provide: glucosamine, MSM, and chondroitin along with a dose of immune-boosting vitamin C.

Key Features:

  • Glucosamine tablets
  • 4 options: 60, 90, 120, or 240 per bottle
  • Contain glucosamine, MSM, chondroitin, vitamin C, and manganese
  • NASC quality seal

PTC Profits to Charity Glucosamine Tablets

PTC Profits to Charity Hip & Joint Support

As the name states, a portion of every purchase goes to charity. These tablets contain glucosamine, MSM, chondroitin, and manganese. This is an all-natural formula produced in the USA, and PTC offers a 90-day satisfaction guarantee.

Key Features:

  • 120, 240, or 480 tablets per bottle
  • Contains glucosamine, chondroitin, MSM, and manganese
  • A portion of each purchase goes to charity
  • All-natural with no preservatives
  • 90-day satisfaction guarantee

Trader Joe’s Glucosamine

Trader Joe's Glucosamine

Trader Joe’s chewable tablets contain the active ingredients glucosamine, chondroitin, and MSM, along with zinc, manganese, and copper. You get 100 chewable tablets per bottle, and Trader Joe’s products are made in the USA.

Key Features:

  • 100 chewable tablets per bottle
  • Made in the USA
  • Contain glucosamine, MSM, chondroitin, zinc, manganese, and copper
  • Recommended dosing instructions

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